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Systematic Reviews & Other Review Types

This guide will help you get started with your next systematic review, scoping review, or other review types.

Other names for a Meta-Syntheses

Meta-synthesis, Meta-ethnography, Qualitative Evidence Synthesis, Qualitative Meta-Synthesis, Meta narrative review (related)

What is a Meta-Syntheses?

A meta-synteses is bringing together qualitative data to form a new interpretation of the research field.  It helps to build new theories and is not to be confused with a meta-analysis which tests a hypothesis using quantitative data.  It primarily generates theory such as program theory, implementation theory, or an explanatory theory of why the intervention works or not, hypothesis for future testing or comparison with trial outcomes.

Meta-syntheses are best designed for:

  • To re-interpret meaning across many qualitative studies.

(Source:  S. Atkins et al (2008))

What is a Meta-Syntheses? Outline of Stages

Timeframe: 12+ months or less.   *Varies beyond the type of review. Depends on many factors such as but not limited to: resources available, the quantity and quality of the literature, and the expertise or experience of reviewers" (Grant et al. 2009)

Question: "A clearly formulated question helps to set boundaries for the scope and depth of a meta-ethnography" (Atkins S.)

Is your review question a complex intervention? Learn more here

Sources and searches: Not as exhaustive as a systematic review, unless the question requires exhaustive searching.  Can search within a particular setting.  Search specifically for qualitative studies if possible (be careful with search filters).  Search may rely more heavily on inclusion and exclusion criteria.

See our Systematic Review Search Service for help conducting the search!

Selection: Different screening process--includes repeated reading of articles to connect and record concepts or themes. 

Appraisal: Focus is on the translation of studies and then systematically compared or 'translated' within and across studies while retaining the structure of the relationships between central concepts/themes and includes a 'thematic analysis'.

Synthesis: Qualitative Differs from a Meta-Analysis (Quantitative) "The goal is not aggregative in the sense of 'adding studies together' as with a meta-analysis.  On the contrary, it is interpretative in broadening understanding of a particular phenomenon." (Source: Grant et al (2009))

There are 3 types of synthesis that may be used.  A second level of synthesis is possible.

  1. Reciprocal Translation: Concepts in one study can incorporate those of another.
  2. Refutational Translation: Concepts in different studies contradict one another.
  3. Line of Argument Synthesis: Studies identify different aspects of the topic that can be drawn together in a new interpretation.

(Source: France EF, Ring N et al (1988))

For more about the reporting guidelines for a Meta-Synthesis or Meta-Ethnography please visit the eMERGe Project website. and also look at ENTREQ for the reporting of qualitative research. 

Also visit the Cochrane Qualitative & Implementation Methods Group

The seven phases of Noblit and Hare's meta-ethnography (meta-syntheses) approach

(Source: France EF, Ring N et al (1988))

Limitations of a Meta-Syntheses

  • Only appropriate for high-quality qualitative studies
  • Can only accommodate a limited number of primary studies, choice of a meta-ethnography may not be confirmed until pool of evidence known
  • Requires significant methodological skill and experience with qualitative methods
  • May take time to engage with the evidence and develop theory
  • Requires further interpretation by policy makers and practitioners

(Source: M. Petticrew et al (2013) and Li T. et al (2001))

For additional help

Systematic Review Service:

The health sciences library Chat with a Librarian service is available at Many of our librarians are available to provide systematic review education. Or you may reach the Team Lead, Stephanie Roth: Email Phone (215) 707-9469