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LKSOM Phase 2/3

Resources for the 3rd year and 4th year LKSOM Clinical Clerkships

Creating a clinical question

Why should you use PICO to define the clinical question?

  • PICO helps you create a focused question and generate keywords to create efficient searches. 

Patient, Population or Problem

How would I describe a group of patients similar to mine?


Which main intervention, exposure, or prognostic factor am I considering?

Comparison (if appropriate)

What is the main alternative to compare with the intervention?


What can I hope to accomplish, measure, improve, affect?

Type of Question 

How would I categorize this question (therapy, diagnosis, prognosis, etiology/harm)?

Type of Study 

What would be the best study design in order to answer this question?

Finding Evidence-Based Answers to Clinical Questions – Quickly and Effectively


Finding Evidence-Based Answers to Clinical Questions - Quickly and Effectively
I need: Example: Resources to consider:

Point of Care tool

(Background question)


What are the symptoms of menopause?


UpToDate (GME)

Background information

(Background question)

I have a new patient with lupus and I need to learn about it




Calculator, Rule, Table, Lab Result, Procedure or Test What is the dosing conversion for lorazepam and diazepam?


Lexi-Comp Online (for drugs)

Practice Guidelines What is the current guideline for management of type 2 diabetes in adults?

What are the recommended screening guidelines for your new patient?

PubMed (use article type filter to limit to "practice guidelines")

Prevention TaskForce Mobile (ePSS)


ECRI Guidelines Trust (requires free registration)

Drug Information Are the two IV infusion drugs, cefazolin and acetaminophen compatible at the Y-site?

Lexi-Comp Online



An answer to a narrower, focused clinical question

(Foreground question)

In a toddler with croup, do glucocorticoids reduce symptoms?

PubMed Clinical Queries

Cochrane Library 

Embase (PICO search option)

Information to Share with Patients Where can I find some nutrition information for my newly-diagnosed patient with diabetes?


Medline Plus

Mayo Clinic 

Lexi-Comp Online


Dermatology  Does this patient have rosacea?

Fitzpatrick's dermatology in general medicine

Dermatology: Skin of Color Guide 


Adapted from Dartmouth College Biomedical Libraries' Finding Evidence-Based Answers to Clinical Questions-Quickly and Effectively